Amperometric Readout and Electrode Array Chip for Bioelectrochemical Sensors

— As nanostructured bioelectronic interfaces continue to evolve for sensor applications, new readout circuits are needed to harness their capabilities. This paper presents a single-chip amperometric readout circuit and electrode array system suitable for bioelectrochemical measurements. The chip features a CMOS potentiostat with high resolution, rangeprogrammable current readout and electrochemical cell potential drive circuitry, which can perform on-chip chronoamperometry and cyclic voltammetry assays. Through post-CMOS fabrication, the surface of the chip is prepared with an array of electrodes suitable for formation of bioelectronic interfaces and on-chip bioelectrochemical measurements. The 3x3mm2 chip nominally hosts a 4x4 working electrode array and supports amperometric outputs ranging from 10pA to 10µA with sub-pA resolution.

• Type: Conference
• Year: 2007
• Where: ISCAS
• Authors: Andrew Mason, Yue Huang, Chao Yang, Jichun Zhang
• Keywords: Electrode Array, ISCAS 2007, Readout Circuit, Single-chip Amperometric Readout