Sciweavers

Share
NCA
2006
IEEE

Analysing the localisation sites of proteins through neural networks ensembles

9 years 10 months ago
Analysing the localisation sites of proteins through neural networks ensembles
Scientists involved in the area of proteomics are currently seeking integrated, customised and validated research solutions to better expedite their work in proteomics analyses and drug discoveries. Some drugs and most of their cell targets are proteins, because proteins dictate biological phenotype. In this context, the automated analysis of protein localisation is more complex than the automated analysis of DNA sequences; nevertheless the benefits to be derived are of same or greater importance. In order to accomplish this target, the right choice of the kind of the methods for these applications, especially when the data set is drastically imbalanced, is very important and crucial. In this paper we investigate the performance of some commonly used classifiers, such as the K nearest neighbours and feed-forward neural networks with and without cross-validation, in a class of imbalanced problems from the bioinformatics domain. Furthermore, we construct ensemble-based schemes using the ...
Aristoklis D. Anastasiadis, George D. Magoulas
Added 14 Dec 2010
Updated 14 Dec 2010
Type Journal
Year 2006
Where NCA
Authors Aristoklis D. Anastasiadis, George D. Magoulas
Comments (0)
books