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1997

Automated Alignment of RNA Sequences to Pseudoknotted Structures

9 years 6 months ago
Automated Alignment of RNA Sequences to Pseudoknotted Structures
Seq7 is a newprogramfor generating multiple structure-based alignments of RNAsequences. Byusing a variant of Dijkstra’s algorithm to find the shortest path through a specially constructed graph, Seq7 is able to align RNAsequences to pseudoknotted structures in polynomial time. In this paper, we describe the operation of Seq7 and demonstrate the program’s abilities. Wealso describe the use of Sex/7 in an Expectation-Maximizationprocedure that automates the process of structural modelingand alignment of RNAsequences.
Jack E. Tabaska, Gary D. Stormo
Added 01 Nov 2010
Updated 01 Nov 2010
Type Conference
Year 1997
Where ISMB
Authors Jack E. Tabaska, Gary D. Stormo
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