Sciweavers

Share
ANOR
2010

A Bayesian approach for the alignment of high-resolution NMR spectra

10 years 4 months ago
A Bayesian approach for the alignment of high-resolution NMR spectra
: The rapid progresses in human genome project and biotechnologies result in the sheer volume of datasets associated with in-depth scientific knowledge. Metabolomics is defined as the study for understanding metabolic process in living systems. Metabolomics approaches that used high-resolution nuclear magnetic resonance (NMR) spectroscopy have been used to characterize metabolic variations in response to physiological alternation, disease states, genetic modification, and nutrition intake. An NMR spectrum usually involves tens of thousands of variables and the comparison of multiple spectra lead to a huge number of data points and a situation that poses a great challenge to analytical and computational capabilities. When considering multiple spectra, small variations due to concentration, pH, and temperature, influence the spectral alignment and thus can interfere with direct comparisons between samples. Thus, it is crucial to align spectra before applying any subsequent statistical an...
Seoung Bum Kim, Zhou Wang, Basavaraj Hiremath
Added 08 Dec 2010
Updated 08 Dec 2010
Type Journal
Year 2010
Where ANOR
Authors Seoung Bum Kim, Zhou Wang, Basavaraj Hiremath
Comments (0)
books