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ICISP
2010
Springer

Classification of High-Resolution NMR Spectra Based on Complex Wavelet Domain Feature Selection and Kernel-Induced Random Forest

10 years 28 days ago
Classification of High-Resolution NMR Spectra Based on Complex Wavelet Domain Feature Selection and Kernel-Induced Random Forest
High-resolution nuclear magnetic resonance (NMR) spectra contain important biomarkers that have potentials for early diagnosis of disease and subsequent monitoring of its progression. Traditional features extraction and analysis methods have been carried out in the original frequency spectrum domain. In this study, we conduct feature selection based on a complex wavelet transform by making use of its energy shift-insensitive property in a multiresolution signal decomposition. A false discovery rate based multiple testing procedure is employed to identify important metabolite features. Furthermore, a novel kernel-induced random forest algorithm is used for the classification of NMR spectra based on the selected features. Our experiments with real NMR spectra showed that the proposed method leads to significant reduction in misclassification rate.
Guangzhe Fan, Zhou Wang, Seoung Bum Kim, Chivalai
Added 19 Jul 2010
Updated 19 Jul 2010
Type Conference
Year 2010
Where ICISP
Authors Guangzhe Fan, Zhou Wang, Seoung Bum Kim, Chivalai Temiyasathit
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