Clinical decision support implemented with academic detailing improves prescribing of key renally cleared drugs in the hospital

Objective Lack of dose adjustment for renally cleared drugs in the presence of poor renal function is a common problem in the hospital setting. The absence of a clinical decision support system (CDSS) from direct clinician workflows such as computerized provider order entry (CPOE) hinders the uptake of CDSS. This study implemented CDSS in an environment independent of CPOE, introduced to prescribers via academic detailing, to address the dosing of renally cleared drugs. Design GFR+ was designed to automatically calculate and update renal function, doses of key drugs adjusted for renal function, and highlight clinically significant decreases in renal function. Prescribers were made aware of GFR+, its navigation, and surrounding clinical issues, using academic detailing. Measurement The rate of dosing conformity and management for key renally cleared drugs in hospitalized patients, before and after GFR+ implementation. Results Improvements were seen in dosing conformity for enoxaparin (...

• Type: Journal
• Year: 2010
• Where: JAMIA
• Authors: Gregory W. Roberts, Christopher J. Farmer, Philip C. Cheney, Stephen M. Govis, Thomas W. Belcher, Scott A. Walsh, Robert J. Adams
• Keywords: Clinical Decision, Drugs, JAMIA 2010, Renal Function