Composing, optimizing, and executing plans for bioinformatics web services

14 years 4 months ago

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The emergence of a large number of bioinformatics datasets on the Internet has resulted in the need for flexible and efficient approaches to integrate information from multiple bioinformatics data sources and services. In this paper, we present our approach to automatically generate composition plans for web services, optimize the composition plans, and execute these plans efficiently. While data integration techniques have been applied to the bioinformatics domain, the focus has been on answering specific user queries. In contrast, we focus on automatically generating parameterized integration plans that can be hosted as web services that respond to a range of inputs. In addition, we present two novel techniques that improve the execution time of the generated plans by reducing the number of requests to the existing data sources and by executing the generated plan more efficiently. The first optimization technique, called tuple-level filtering, analyzes the source/service descriptions...

Snehal Thakkar, José Luis Ambite, Craig A. Knoblo

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