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BMCBI
2005

COPASAAR - A database for proteomic analysis of single amino acid repeats

10 years 2 months ago
COPASAAR - A database for proteomic analysis of single amino acid repeats
Background: Single amino acid repeats make up a significant proportion in all of the proteomes that have currently been determined. They have been shown to be functionally and medically significant, and are associated with cancers and neuro-degenerative diseases such as Huntington's Chorea, where a poly-glutamine repeat is responsible for causing the disease. The COPASAAR database is a new tool to facilitate the rapid analysis of single amino acid repeats at a proteome level. The database aims to simplify the comparison of repeat distributions between proteomes in order to provide a better understanding of their function and evolution. Results: A comparative analysis of all proteomes in the database (currently 244) shows that single amino acid repeats account for about 12
Daniel P. Depledge, Andrew R. Dalby
Added 15 Dec 2010
Updated 15 Dec 2010
Type Journal
Year 2005
Where BMCBI
Authors Daniel P. Depledge, Andrew R. Dalby
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