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CIDR
2009

Data Management for High-Throughput Genomics

9 years 8 months ago
Data Management for High-Throughput Genomics
Today's sequencing technology allows sequencing an individual genome within a few weeks for a fraction of the costs of the original Human Genome project. Genomics labs are faced with dozens of TB of data per week that have to be automatically processed and made available to scientists for further analysis. This paper explores the potential and the limitations of using relational database systems as the data processing platform for high-throughput genomics. In particular, we are interested in the storage management for high-throughput sequence data and in leveraging SQL and user-defined functions for data analysis inside a database system. We give an overview of a database design for high-throughput genomics, how we used a SQL Server database in some unconventional ways to prototype this scenario, and we will discuss some initial findings about the scalability and performance of such a more database-centric approach.
Uwe Röhm, José A. Blakeley
Added 08 Nov 2010
Updated 08 Nov 2010
Type Conference
Year 2009
Where CIDR
Authors Uwe Röhm, José A. Blakeley
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