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CORR
2010
Springer

Detecting Inconsistencies in Large Biological Networks with Answer Set Programming

11 years 5 months ago
Detecting Inconsistencies in Large Biological Networks with Answer Set Programming
Abstract. We introduce an approach to detecting inconsistencies in large biological networks by using Answer Set Programming. To this end, we build upon a recently proposed notion of consistency between biochemical/genetic reactions and high-throughput profiles of cell activity. We then present an approach based on Answer Set Programming to check the consistency of large-scale data sets. Moreover, we extend this methodology to provide explanations for inconsistencies in the data by determining minimal representations of conflicts. In practice, this can be used to identify unreliable data or to indicate missing reactions.
Martin Gebser, Torsten Schaub, Sven Thiele, Philip
Added 09 Dec 2010
Updated 09 Dec 2010
Type Journal
Year 2010
Where CORR
Authors Martin Gebser, Torsten Schaub, Sven Thiele, Philippe Veber
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