DISCO: A Coherent Diffeomorphic Framework for Brain Registration under Exhaustive Sulcal Constraints

Abstract. Neuroimaging at the group level requires spatial normalization of individual structural data. We propose a geometric approach that consists in matching a series of cortical surfaces through diffeomorphic registration of their sulcal imprints. The resulting 3D transforms naturally extends to the entire MRI volumes. The DIffeomorphic Sulcal-based COrtical (DISCO) registration integrates two recent technical outcomes: 1) the automatic extraction, identification and simplification of numerous sulci from T1-weighted MRI data series hereby revealing the sulcal imprint and 2) the measure-based diffeomorphic registration of those crucial anatomical landmarks. We show how the DISCO registration may be used to elaborate a sulcal template which optimizes the distribution of constraints over the entire cortical ribbon. DISCO was evaluated through a group of 20 individual brains. Quantitative and qualitative indices attest how this approach may improve both alignment of sulcal folds and o...

• Type: Conference
• Year: 2009
• Where: MICCAI
• Authors: Guillaume Auzias, Joan Glaunes, Olivier Colliot, Matthieu Perrot, Jean-François Mangin, Alain Trouvé, Sylvain Baillet
• Keywords: DISCO Registration, Entire Cortical Ribbon, Entire Mri Volumes, Medical Imaging, MICCAI 2009