Efficient selection of unique and popular oligos for large EST databases

EST databases have grown exponentially in recent years and now represent the largest collection of genetic sequences. An important application of these databases is that they contain information useful for the design of gene-specific oligonucleotides (or simply, oligos) that can be used in PCR primer design, microarray experiments, and genomic library screening. In this paper, we study two complementary problems concerning the selection of short oligos, e.g., 20

• Type: Journal
• Year: 2004
• Where: BIOINFORMATICS
• Authors: Jie Zheng, Timothy J. Close, Tao Jiang, Stefano Lonardi
• Keywords: BIOINFORMATICS 2004, Database, Est Sequence, Oligos