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2000
Springer

Engineered Communications for Microbial Robotics

12 years 2 months ago
Engineered Communications for Microbial Robotics
Multicellular organisms create complex patterned structures from identical, unreliable components. Learning how to engineer such robust behavior is important to both an improved understanding of computer science and to a better understanding of the natural developmental process. Earlier work by our colleagues and ourselves on amorphous computing demonstrates in simulation how one might build complex patterned behavior in this way. This work reports on our first efforts to engineer microbial cells to exhibit this kind of multicellular pattern directed behavior. We describe a specific natural system, the Lux operon of Vibrio fischeri, which exhibits density dependent behavior using a well characterized set of genetic components. We have isolated, sequenced, and used these components to engineer intercellular communication mechanisms between living bacterial cells. In combination with digitally controlled intracellular genetic circuits, we believe this work allows us to begin the more...
Ron Weiss, Thomas F. Knight Jr.
Added 02 Aug 2010
Updated 02 Aug 2010
Type Conference
Year 2000
Where DNA
Authors Ron Weiss, Thomas F. Knight Jr.
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