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MICCAI
2010
Springer

Estimating Local Surface Complexity Maps Using Spherical Harmonic Reconstructions

9 years 2 months ago
Estimating Local Surface Complexity Maps Using Spherical Harmonic Reconstructions
Abstract. Cortical surface complexity is a potential structural marker for certain diseases such as schizophrenia. In this study, we developed a measure of fractal dimension (FD) calculated from lowpass-filtered spherical harmonic brain surface reconstructions. A local FD measure was also computed at each vertex in a cortical surface mesh, visualizing local variations in surface complexity over the brain surface. We analyzed the surface complexity for 87 patients with DSM-IV schizophrenia (with stable psychopathology and treated with antipsychotic medication) and 108 matched healthy controls. The global FD for the right hemisphere in the schizophrenic group was significantly lower than that in controls. Local FD maps showed that the lower complexity was mainly due to differences in the prefrontal cortex.
Rachel Aine Yotter, Paul M. Thompson, Igor Nenadic
Added 29 Jan 2011
Updated 29 Jan 2011
Type Journal
Year 2010
Where MICCAI
Authors Rachel Aine Yotter, Paul M. Thompson, Igor Nenadic, Christian Gaser
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