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JCNS
2010

Experimental validation of the influence of white matter anisotropy on the intracranial EEG forward solution

11 years 8 months ago
Experimental validation of the influence of white matter anisotropy on the intracranial EEG forward solution
Abstract Forward solutions with different levels of complexity are employed for localization of current generators, which are responsible for the electric and magnetic fields measured from the human brain. The influence of brain anisotropy on the forward solution is poorly understood. The goal of this study is to validate an anisotropic model for the intracranial electric forward solution by comparing with the directly measured `gold standard'. Dipolar sources are created at known locations in the brain and intracranial electroencephalogram (EEG) is recorded simultaneously. Isotropic models with increasing level of complexity are generated along with anisotropic models based on Diffusion tensor imaging (DTI). A Finite Element Method based forward solution is calculated and validated using the measured data. Major findings are (1) An anisotropic model with a linear scaling between the eigenvalues of the electrical conductivity tensor and water self-diffusion tensor in brain tissue ...
Nitin B. Bangera, Donald L. Schomer, Nima Dehghani
Added 19 May 2011
Updated 19 May 2011
Type Journal
Year 2010
Where JCNS
Authors Nitin B. Bangera, Donald L. Schomer, Nima Dehghani, Istvan Ulbert, Sydney S. Cash, Steve Papavasiliou, Solomon R. Eisenberg, Anders M. Dale, Eric Halgren
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