Sciweavers

CORR
2008
Springer

Fabrication of Nanostructured PLGA Scaffolds Using Anodic Aluminum Oxide Templates

13 years 3 months ago
Fabrication of Nanostructured PLGA Scaffolds Using Anodic Aluminum Oxide Templates
PLGA (poly(lactic-co-glycolic acid)) is one of the most used biodegradable and biocompatible materials. Nanostructured PLGA even has great application potentials in tissue engineering. In this research, a fabrication technique for nanostructured PLGA membrane was investigated and developed. In this novel fabrication approach, an anodic aluminum oxide (AAO) film was use as the template; the PLGA solution was then cast on it; the vacuum air-extraction process was applied to transfer the nano porous pattern from the AAO membrane to the PLGA membrane and form nanostures on it. The cell culture experiments of the bovine endothelial cells demonstrated that the nanostructured PLGA membrane can double the cell growing rate. Compared to the conventional chemical-etching process, the physical fabrication method proposed in this research not only is simpler but also does not alter the characteristics of the PLGA. The nanostructure of the PLGA membrane can be well controlled by the AAO temperate.
Cheng-Chih Hsueh, Gou-Jen Wang, Shan-Hui Hsu, Huey
Added 09 Dec 2010
Updated 09 Dec 2010
Type Journal
Year 2008
Where CORR
Authors Cheng-Chih Hsueh, Gou-Jen Wang, Shan-Hui Hsu, Huey-Shan Hung
Comments (0)