Finding the Key to a Synapse

10 years 2 months ago
Finding the Key to a Synapse
Experimental data have shown that synapses are heterogeneous: different synapses respond with different sequences of amplitudes of postsynaptic responses to the same spike train. Neither the role of synaptic dynamics itself nor the role of the heterogeneity of synaptic dynamics for computations in neural circuits is well understood. We present in this article methods that make it feasible to compute for a given synapse with known synaptic parameters the spike train that is optimally fitted to the synapse, for example in the sense that it produces the largest sum of postsynaptic responses. To our surprise we find that most of these optimally fitted spike trains match common firing patterns of specific types of neurons that are discussed in the literature.
Thomas Natschläger, Wolfgang Maass
Added 01 Nov 2010
Updated 01 Nov 2010
Type Conference
Year 2000
Where NIPS
Authors Thomas Natschläger, Wolfgang Maass
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