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MICCAI
2008
Springer

Findings in Schizophrenia by Tract-Oriented DT-MRI Analysis

10 years 1 months ago
Findings in Schizophrenia by Tract-Oriented DT-MRI Analysis
Abstract. This paper presents a tract-oriented analysis of diffusion tensor (DT) images of the human brain. We demonstrate that unlike the commonly used ROI-based methods for population studies, our technique is sensitive to the local variation of diffusivity parameters along the fiber tracts. We show the strength of the proposed approach in identifying the differences in schizophrenic data compared to controls. Statistically significant drops in fractional anisotropy are observed along the genu and bilaterally in the splenium, as well as an increase in principal eigenvalue in uncinate fasciculus. This is the first tract-oriented clinical study in which an anatomical atlas is used to guide the algorithm.
Mahnaz Maddah, Marek Kubicki, William M. Wells I
Added 06 Nov 2009
Updated 06 Nov 2009
Type Conference
Year 2008
Where MICCAI
Authors Mahnaz Maddah, Marek Kubicki, William M. Wells III, Carl-Fredrik Westin, Martha Elizabeth Shenton, W. Eric L. Grimson
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