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BMCBI
2010

GeneMesh: a web-based microarray analysis tool for relating differentially expressed genes to MeSH terms

9 years 1 months ago
GeneMesh: a web-based microarray analysis tool for relating differentially expressed genes to MeSH terms
Background: An important objective of DNA microarray-based gene expression experimentation is determining interrelationships that exist between differentially expressed genes and biological processes, molecular functions, cellular components, signaling pathways, physiologic processes and diseases. Results: Here we describe GeneMesh, a web-based program that facilitates analysis of DNA microarray gene expression data. GeneMesh relates genes in a query set to categories available in the Medical Subject Headings (MeSH) hierarchical index. The interface enables hypothesis driven relational analysis to a specific MeSH subcategory (e.g., Cardiovascular System, Genetic Processes, Immune System Diseases etc.) or unbiased relational analysis to broader MeSH categories (e.g., Anatomy, Biological Sciences, Disease etc.). Genes found associated with a given MeSH category are dynamically linked to facilitate tabular and graphical depiction of Entrez Gene information, Gene Ontology information, KEG...
Saurin D. Jani, Gary L. Argraves, Jeremy L. Barth,
Added 08 Dec 2010
Updated 08 Dec 2010
Type Journal
Year 2010
Where BMCBI
Authors Saurin D. Jani, Gary L. Argraves, Jeremy L. Barth, W. Scott Argraves
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