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2012

iCircos: visual analytics for translational bioinformatics

9 years 7 months ago
iCircos: visual analytics for translational bioinformatics
Translational bioinformatics increasingly involves the discovery of associations between molecular and phenotype information, with the goal of transforming those discoveries into novel methods for diagnosis and treatment. To enable such complex analyses, researchers need approaches that provide the simultaneous representation and interactive analysis of patients, and their molecular and phenotype information. Because few existing visual analytical systems provide appropriate capabilities, we developed a prototypical visual analytical system called iCircos, which enables the simultaneous and interactive exploration of molecular and phenotype information. We discuss our overall method for developing the prototype by integrating user needs and design heuristics from visual analytics, with agile programming in HTML5 and SVG. A demonstration of the prototype to explore molecular and phenotype associations in two disease datasets suggests that iCircos has the potential to accelerate transla...
Suresh K. Bhavnani, Mamta Abbas, Vickie McMicken,
Added 24 Apr 2012
Updated 24 Apr 2012
Type Journal
Year 2012
Where IHI
Authors Suresh K. Bhavnani, Mamta Abbas, Vickie McMicken, Numan Oezguen, Jeffry A. Tupa
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