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IJON
2006

Inhibitory control of spike timing precision

13 years 3 months ago
Inhibitory control of spike timing precision
GABAergic inhibition via local interneurons may play a role in enhancing spike timing precision in principal cells, since it tends to eliminate the influence of initial conditions. However, both the number and the timing of inhibitory synaptic events may be variable across repeated trials. How does this variability affect the spike timing precision in principal neurons ? In this paper, we derive an analytical expression for the spike output jitter as a function of the variability of the received inhibition. This study predicts that variable inhibition is especially tolerated as the number of inhibitory cells is large, which is consistent with experimental data from early olfactory systems (antennal lobe for insects, olfactory bulb for vertebrates).
Maxime Ambard, Dominique Martinez
Added 13 Dec 2010
Updated 13 Dec 2010
Type Journal
Year 2006
Where IJON
Authors Maxime Ambard, Dominique Martinez
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