Interacting Slow and Fast Dynamics in Precise Spiking-Bursting Neurons

We have explored the role of the interaction of slow and fast intracellular dynamics in generating precise spiking-bursting activity in a model of the heartbeat central pattern generator of the leech. In particular we study the effect of calcium-dependent currents on the neural signatures generated in the circuit. These neural signatures are cell-specific interspike intervals in the spiking-bursting activity of each neuron. Our results show that the slow dynamics of intracelullar calcium concentration can regulate the precision and shape of the neural signatures.

• Type: Conference
• Year: 2005
• Where: IWINAC
• Authors: Fabiano Baroni, Joaquín J. Torres, Pablo Varona
• Keywords: Fast Intracellular Dynamics, IWINAC 2005, Neural Signatures, Spiking-bursting Activity