Ontology-based Queries over Cancer Data

10 years 1 months ago
Ontology-based Queries over Cancer Data
The ever-increasing amount of data in biomedical research, and in cancer research in particular, needs to be managed to support efficient data access, exchange and integration. Existing software infrastructures, such caGrid, support access to distributed information annotated with a domain ontology. However, caGrid's current querying functionality depends on the structure of individual data resources without exploiting the semantic annotations. In this paper, we present the design and development of an ontology-based querying functionality that consists of: the generation of OWL2 ontologies from the underlying data resources metadata and a query rewriting and translation process based on reasoning, which converts a query at the domain ontology level into queries at the software infrastructure level. We present a detailed analysis of our approach as well as an extensive performance evaluation. While the implementation and evaluation were performed for the caGrid infrastructure, the...
Alejandra González Beltrán, Ben Tagg
Added 01 Mar 2011
Updated 01 Mar 2011
Type Journal
Year 2010
Where CORR
Authors Alejandra González Beltrán, Ben Tagger, Anthony Finkelstein
Comments (0)