Sciweavers

Share
TMI
2008

ORBIT: A Multiresolution Framework for Deformable Registration of Brain Tumor Images

10 years 10 months ago
ORBIT: A Multiresolution Framework for Deformable Registration of Brain Tumor Images
Abstract--A deformable registration method is proposed for registering a normal brain atlas with images of brain tumor patients. The registration is facilitated by first simulating the tumor mass effect in the normal atlas in order to create an atlas image that is as similar as possible to the patient's image. An optimization framework is used to optimize the location of tumor seed as well as other parameters of the tumor growth model, based on the pattern of deformation around the tumor region. In particular, the optimization is implemented in a multiresolution and hierarchical scheme, and it is accelerated by using a principal component analysis (PCA)-based model of tumor growth and mass effect, trained on a computationally more expensive biomechanical model. Validation on simulated and real images shows that the proposed registration framework, referred to as ORBIT (optimization of tumor parameters and registration of brain images with tumors), outperforms other available regis...
Evangelia I. Zacharaki, Dinggang Shen, Seung-koo L
Added 15 Dec 2010
Updated 15 Dec 2010
Type Journal
Year 2008
Where TMI
Authors Evangelia I. Zacharaki, Dinggang Shen, Seung-koo Lee, Christos Davatzikos
Comments (0)
books