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RECOMB
2005
Springer

A Practical Approach to Significance Assessment in Alignment with Gaps

14 years 3 months ago
A Practical Approach to Significance Assessment in Alignment with Gaps
Abstract. Current numerical methods for assessing the statistical significance of local alignments with gaps are time consuming. Analytical solutions thus far have been limited to specific cases. Here, we present a new line of attack to the problem of statistical significance assessment. We combine this new approach with known properties of the dynamics of the global alignment algorithm and high performance numerical techniques and present a novel method for assessing significance of gaps within practical time scales. The results and performance of these new methods test very well against tried methods with drastically less effort.
Nicholas Chia, Ralf Bundschuh
Added 03 Dec 2009
Updated 03 Dec 2009
Type Conference
Year 2005
Where RECOMB
Authors Nicholas Chia, Ralf Bundschuh
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