Sciweavers

Share
NAR
2002

Recent improvements to the SMART domain-based sequence annotation resource

8 years 11 months ago
Recent improvements to the SMART domain-based sequence annotation resource
SMART (Simple Modular Architecture Research Tool, http://smart.embl-heidelberg.de) is a web-based resource used for the annotation of protein domains and the analysis of domain architectures, with particular emphasis on mobile eukaryotic domains. Extensive annotation for each domain family is available, providing information relating to function, subcellular localization, phyletic distribution and tertiary structure. The January 2002 release has added more than 200 hand-curated domain models. This brings the total to over 600 domain families that are widely represented among nuclear, signalling and extracellular proteins. Annotation now includes links to the Online Mendelian Inheritance in Man (OMIM) database in cases where a human disease is associated with one or more mutations in a particular domain. We have implemented new analysis methods and updated others. New advanced queries provide direct access to the SMART relational database using SQL. This database now contains informati...
Ivica Letunic, Leo Goodstadt, Nicholas J. Dickens,
Added 22 Dec 2010
Updated 22 Dec 2010
Type Journal
Year 2002
Where NAR
Authors Ivica Letunic, Leo Goodstadt, Nicholas J. Dickens, Tobias Doerks, Jörg Schultz, Richard Mott, Francesca Ciccarelli, Richard R. Copley, Chris P. Ponting, Peer Bork
Comments (0)
books