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2000
Springer

Structure Motif Discovery and Mining the PDB

12 years 3 months ago
Structure Motif Discovery and Mining the PDB
We describe an algorithm for the automatic discovery of recurring patterns in protein structures. The patterns consist of individual residues having a defined order along the protein's backbone that come close together in the structure and whose spatial conformations are similar. The residues in a pattern need not be close in the protein's sequence. The work described in this paper builds on an earlier reported algorithm for motif discovery. This paper describes a significant improvement of the algorithm which makes it very efficient. The improved efficiency allows us to use it for doing unsupervised learning of patterns occurring in small subsets in a large set of structures, a non-redundant subset of the PDB database of all known protein structures.
Inge Jonassen, Ingvar Eidhammer, Darrell Conklin,
Added 24 Aug 2010
Updated 24 Aug 2010
Type Conference
Year 2000
Where GCB
Authors Inge Jonassen, Ingvar Eidhammer, Darrell Conklin, William R. Taylor
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