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ICASSP
2011
IEEE

Time-varying lung ventilation analysis of 4DCT using image registration

10 years 12 months ago
Time-varying lung ventilation analysis of 4DCT using image registration
Imaging techniques for measuring lung ventilation are essential tools to study lung tissue response to radiation therapy. Most of the existing CT and image registration based ventilation measurement methods use two extreme phases (end expiration and end inspiration) while ignoring the important ventilation variation within the respiratory cycle. In this paper, we present a new instantaneous ventilation measurement scheme using multiple 4DCT phase images and regularized 3D image registration, which aims at measuring the regional ventilation within the respiratory cycle. The ventilation is measured using the Jacobian (a function of local partial derivatives) of the registration displacement field. For all four animals, 39% of the total lung volume reaches maximum ventilation at T2 (50% inspiration phase) during inspiration and the 75% of the total lung volume reaches maximum ventilation at T5 (75% expiration phase) during expiration. The registration accuracy assessed by 200 semiautoma...
Kai Ding, Kaifang Du, Kunlin Cao, Gary E. Christen
Added 20 Aug 2011
Updated 20 Aug 2011
Type Journal
Year 2011
Where ICASSP
Authors Kai Ding, Kaifang Du, Kunlin Cao, Gary E. Christensen, Joseph M. Reinhardt
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