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BMCBI
2008
228views more  BMCBI 2008»
13 years 6 months ago
Adaptive diffusion kernel learning from biological networks for protein function prediction
Background: Machine-learning tools have gained considerable attention during the last few years for analyzing biological networks for protein function prediction. Kernel methods a...
Liang Sun, Shuiwang Ji, Jieping Ye
BMCBI
2006
172views more  BMCBI 2006»
13 years 6 months ago
Prediction of cis/trans isomerization in proteins using PSI-BLAST profiles and secondary structure information
Background: The majority of peptide bonds in proteins are found to occur in the trans conformation. However, for proline residues, a considerable fraction of Prolyl peptide bonds ...
Jiangning Song, Kevin Burrage, Zheng Yuan, Thomas ...
BMCBI
2006
143views more  BMCBI 2006»
13 years 6 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
KES
2008
Springer
13 years 6 months ago
Downsizing Multigenic Predictors of the Response to Preoperative Chemotherapy in Breast Cancer
We present a method for designing efficient multigenic predictors with few probes and its application to the prediction of the response to preoperative chemotherapy in breast cance...
René Natowicz, Roberto Incitti, Roman Rouzi...
BMCBI
2004
176views more  BMCBI 2004»
13 years 6 months ago
Boosting accuracy of automated classification of fluorescence microscope images for location proteomics
Background: Detailed knowledge of the subcellular location of each expressed protein is critical to a full understanding of its function. Fluorescence microscopy, in combination w...
Kai Huang, Robert F. Murphy