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» A Bernoulli-Gaussian model for gene factor analysis
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BMCBI
2002
214views more  BMCBI 2002»
13 years 5 months ago
Automated modelling of signal transduction networks
Background: Intracellular signal transduction is achieved by networks of proteins and small molecules that transmit information from the cell surface to the nucleus, where they ul...
Martin Steffen, Allegra Petti, John Aach, Patrik D...
BMCBI
2007
155views more  BMCBI 2007»
13 years 5 months ago
ProCMD: a database and 3D web resource for protein C mutants
Background: Activated Protein C (ProC) is an anticoagulant plasma serine protease which also plays an important role in controlling inflammation and cell proliferation. Several mu...
Pasqualina D'Ursi, Francesca Marino, Andrea Caprer...
BMCBI
2005
112views more  BMCBI 2005»
13 years 5 months ago
"Harshlighting" small blemishes on microarrays
Background: Microscopists are familiar with many blemishes that fluorescence images can have due to dust and debris, glass flaws, uneven distribution of fluids or surface coatings...
Mayte Suárez-Fariñas, Asifa Haider, ...
HYBRID
2004
Springer
13 years 10 months ago
Modeling Subtilin Production in Bacillus subtilis Using Stochastic Hybrid Systems
The genetic network regulating the biosynthesis of subtilin in Bacillus subtilis is modeled as a stochastic hybrid system. The continuous state of the hybrid system is the concentr...
Jianghai Hu, Wei Chung Wu, Shankar Sastry
ICCSA
2005
Springer
13 years 11 months ago
A Penalized Likelihood Estimation on Transcriptional Module-Based Clustering
In this paper, we propose a new clustering procedure for high dimensional microarray data. Major difficulty in cluster analysis of microarray data is that the number of samples to ...
Ryo Yoshida, Seiya Imoto, Tomoyuki Higuchi