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» A Case for Codons in Evolutionary Algorithms
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GECCO
2003
Springer
13 years 10 months ago
A Case for Codons in Evolutionary Algorithms
A new method is developed for representation and encoding in population-based evolutionary algorithms. The method is inspired by the biological genetic code and utilizes a many-to-...
Joshua Gilbert, Margaret J. Eppstein
BMCBI
2010
150views more  BMCBI 2010»
13 years 5 months ago
Evolutionary rates at codon sites may be used to align sequences and infer protein domain function
Background: Sequence alignments form part of many investigations in molecular biology, including the determination of phylogenetic relationships, the prediction of protein structu...
Pierre M. Durand, Scott Hazelhurst, Theresa L. Coe...
BMCBI
2011
12 years 12 months ago
Simulated evolution applied to study the genetic code optimality using a model of codon reassignments
Background: As the canonical code is not universal, different theories about its origin and organization have appeared. The optimization or level of adaptation of the canonical ge...
Jose Santos, Ángel Monteagudo
BMCBI
2007
104views more  BMCBI 2007»
13 years 5 months ago
Identification of putative regulatory upstream ORFs in the yeast genome using heuristics and evolutionary conservation
Background: The translational efficiency of an mRNA can be modulated by upstream open reading frames (uORFs) present in certain genes. A uORF can attenuate translation of the main...
Marija Cvijovic, Daniel Dalevi, Elizabeth Bilsland...
BMCBI
2008
111views more  BMCBI 2008»
13 years 5 months ago
GENOMEPOP: A program to simulate genomes in populations
Background: There are several situations in population biology research where simulating DNA sequences is useful. Simulation of biological populations under different evolutionary...
Antonio Carvajal-Rodríguez