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BMCBI
2005
13 years 5 months ago
2005
Background: With the exponential increase in genomic sequence data there is a need to develop automated approaches to deducing the biological functions of novel sequences with hig...
BMCBI
2005
13 years 5 months ago
2005
Background: Transcription factor binding site (TFBS) prediction is a difficult problem, which requires a good scoring function to discriminate between real binding sites and backg...
LREC
2010
13 years 7 months ago
2010
Automatic acquisition of novel compounds is notoriously difficult because most novel compounds have relatively low frequency in a corpus. The current study proposes a new method t...
BMCBI
2010
2010
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
13 years 5 months ago
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
BMCBI
2010
13 years 5 months ago
2010
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...