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JCB
2006
114views more  JCB 2006»
13 years 4 months ago
A General Modeling Strategy for Gene Regulatory Networks with Stochastic Dynamics
A stochastic genetic toggle switch model that consists of two identical, mutually repressive genes is built using the Gillespie algorithm with time delays as an example of a simpl...
Andre Ribeiro, Rui Zhu, Stuart A. Kauffman
CEC
2003
IEEE
13 years 9 months ago
Stochastic neural network models for gene regulatory networks
AbstractRecent advances in gene-expression profiling technologies provide large amounts of gene expression data. This raises the possibility for a functional understanding of geno...
Tianhai Tian, Kevin Burrage
JCB
2002
131views more  JCB 2002»
13 years 4 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong
CMSB
2006
Springer
13 years 8 months ago
Regulatory Network Reconstruction Using Stochastic Logical Networks
Abstract. This paper presents a method for regulatory network reconstruction from experimental data. We propose a mathematical model for regulatory interactions, based on the work ...
Bartek Wilczynski, Jerzy Tiuryn
BMCBI
2006
127views more  BMCBI 2006»
13 years 4 months ago
On the attenuation and amplification of molecular noise in genetic regulatory networks
Background: Noise has many important roles in cellular genetic regulatory functions at the nanomolar scale. At present, no good theory exists for identifying all possible mechanis...
Bor-Sen Chen, Yu-Chao Wang