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» A Geometric Representation of Protein Sequences
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BMCBI
2008
163views more  BMCBI 2008»
13 years 6 months ago
ProfileGrids as a new visual representation of large multiple sequence alignments: a case study of the RecA protein family
Background: Multiple sequence alignments are a fundamental tool for the comparative analysis of proteins and nucleic acids. However, large data sets are no longer manageable for v...
Alberto I. Roca, Albert E. Almada, Aaron C. Abajia...
CIKM
2009
Springer
14 years 16 days ago
Linear predictive coding representation of correlated mutation for protein sequence alignment
Background: Although both conservation and correlated mutation (CM) are important information reflecting the different sorts of context in multiple sequence alignment, most of ali...
Chan-seok Jeong, Dongsup Kim
BMCBI
2006
96views more  BMCBI 2006»
13 years 6 months ago
Structure alignment based on coding of local geometric measures
Background: A structure alignment method based on a local geometric property is presented and its performance is tested in pairwise and multiple structure alignments. In this appr...
Peter L. Chang, Andrew W. Rinne, T. Gregory Dewey
BMCBI
2011
12 years 9 months ago
In-silico prediction of disorder content using hybrid sequence representation
Background: Intrinsically disordered proteins play important roles in various cellular activities and their prevalence was implicated in a number of human diseases. The knowledge ...
Marcin J. Mizianty, Tuo Zhang, Bin Xue, Yaoqi Zhou...
EUROGP
2006
Springer
137views Optimization» more  EUROGP 2006»
13 years 9 months ago
Geometric Crossover for Biological Sequences
This paper extends a geometric framework for interpreting crossover and mutation [4] to the case of sequences. This representation is important because it is the link between artif...
Alberto Moraglio, Riccardo Poli, Rolv Seehuus