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BMCBI
2006
115views more  BMCBI 2006»
13 years 5 months ago
Multivariate curve resolution of time course microarray data
Background: Modeling of gene expression data from time course experiments often involves the use of linear models such as those obtained from principal component analysis (PCA), i...
Peter D. Wentzell, Tobias K. Karakach, Sushmita Ro...
BMCBI
2006
130views more  BMCBI 2006»
13 years 5 months ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
ECCC
2007
122views more  ECCC 2007»
13 years 5 months ago
Infeasibility of Instance Compression and Succinct PCPs for NP
The OR-SAT problem asks, given Boolean formulae φ1, . . . , φm each of size at most n, whether at least one of the φi’s is satisfiable. We show that there is no reduction fr...
Lance Fortnow, Rahul Santhanam
BMCBI
2005
67views more  BMCBI 2005»
13 years 4 months ago
Sequence signature analysis of chromosome identity in three Drosophila species
Background: All eukaryotic organisms need to distinguish each of their chromosomes. A few protein complexes have been described that recognise entire, specific chromosomes, for in...
Per Stenberg, Fredrik Pettersson, Anja O. Saura, A...
JKM
2007
126views more  JKM 2007»
13 years 4 months ago
The moderating role of human capital management practices on employee capabilities
Purpose – The purpose of this paper is to suggest and empirically test a model that explains employee capabilities from the knowledge-based perspective. In this model, human cap...
Nick Bontis, Alexander Serenko