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BMCBI
2011
13 years 13 days ago
NClassG+: A classifier for non-classically secreted Gram-positive bacterial proteins
Background: Most predictive methods currently available for the identification of protein secretion mechanisms have focused on classically secreted proteins. In fact, only two met...
Daniel Restrepo-Montoya, Camilo Pino, Luis F. Ni&n...
BMCBI
2011
12 years 9 months ago
Dissecting protein loops with a statistical scalpel suggests a functional implication of some structural motifs
Background: One of the strategies for protein function annotation is to search particular structural motifs that are known to be shared by proteins with a given function. Results:...
Leslie Regad, Juliette Martin, Anne-Claude Camprou...
BMCBI
2010
159views more  BMCBI 2010»
13 years 5 months ago
Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines
Background: Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods ha...
Alvaro J. González, Li Liao
BMCBI
2004
111views more  BMCBI 2004»
13 years 5 months ago
The Hotdog fold: wrapping up a superfamily of thioesterases and dehydratases
Background: The Hotdog fold was initially identified in the structure of Escherichia coli FabA and subsequently in 4-hydroxybenzoyl-CoA thioesterase from Pseudomonas sp. strain CB...
Shane C. Dillon, Alex Bateman
BMCBI
2008
98views more  BMCBI 2008»
13 years 5 months ago
PredGPI: a GPI-anchor predictor
Background: Several eukaryotic proteins associated to the extracellular leaflet of the plasma membrane carry a Glycosylphosphatidylinositol (GPI) anchor, which is linked to the C-...
Andrea Pierleoni, Pier Luigi Martelli, Rita Casadi...