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BMCBI
2008
211views more  BMCBI 2008»
13 years 4 months ago
CPSP-tools - Exact and complete algorithms for high-throughput 3D lattice protein studies
Background: The principles of protein folding and evolution pose problems of very high inherent complexity. Often these problems are tackled using simplified protein models, e.g. ...
Martin Mann, Sebastian Will, Rolf Backofen
EVOW
2004
Springer
13 years 10 months ago
A Memetic Algorithm for Protein Structure Prediction in a 3D-Lattice HP Model
This paper presents a memetic algorithm with self-adaptive local search, applied to protein structure prediction in an HP, cubiclattice model. Besides describing in detail how the ...
Andrea Bazzoli, Andrea Tettamanzi
CEC
2011
IEEE
12 years 4 months ago
Comparing alternative energy functions for the HP model of protein structure prediction
Abstract—Protein structure prediction is the problem of finding the functional conformation of a protein given only its amino uence. The HP lattice model is an abstract formulat...
Mario Garza-Fabre, Eduardo Rodriguez-Tello, Gregor...
BMCBI
2007
216views more  BMCBI 2007»
13 years 4 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos
EVOW
2012
Springer
12 years 15 days ago
Multiobjectivizing the HP Model for Protein Structure Prediction
Abstract. The hydrophobic-polar (HP) model for protein structure preabstracts the fact that hydrophobic interactions are a dominant force in the protein folding process. This model...
Mario Garza-Fabre, Eduardo Rodriguez-Tello, Gregor...