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JMLR
2008
141views more  JMLR 2008»
13 years 4 months ago
Graphical Methods for Efficient Likelihood Inference in Gaussian Covariance Models
In graphical modelling, a bi-directed graph encodes marginal independences among random variables that are identified with the vertices of the graph. We show how to transform a bi...
Mathias Drton, Thomas S. Richardson
TSP
2010
12 years 11 months ago
Gaussian multiresolution models: exploiting sparse Markov and covariance structure
We consider the problem of learning Gaussian multiresolution (MR) models in which data are only available at the finest scale and the coarser, hidden variables serve both to captu...
Myung Jin Choi, Venkat Chandrasekaran, Alan S. Wil...
BMCBI
2006
161views more  BMCBI 2006»
13 years 4 months ago
A novel approach to phylogenetic tree construction using stochastic optimization and clustering
Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
Ling Qin, Yixin Chen, Yi Pan, Ling Chen
BMCBI
2008
128views more  BMCBI 2008»
13 years 5 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson