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BMCBI
2010
115views more  BMCBI 2010»
13 years 6 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
BMCBI
2010
146views more  BMCBI 2010»
13 years 6 months ago
Revealing and avoiding bias in semantic similarity scores for protein pairs
Background: Semantic similarity scores for protein pairs are widely applied in functional genomic researches for finding functional clusters of proteins, predicting protein functi...
Jing Wang 0004, Xianxiao Zhou, Jing Zhu, Chenggui ...
AIIA
2009
Springer
14 years 28 days ago
Ontology-Driven Co-clustering of Gene Expression Data
Abstract. The huge volume of gene expression data produced by microarrays and other high-throughput techniques has encouraged the development of new computational techniques to eva...
Francesca Cordero, Ruggero G. Pensa, Alessia Visco...
BMCBI
2006
117views more  BMCBI 2006»
13 years 6 months ago
SigFlux: A novel network feature to evaluate the importance of proteins in signal transduction networks
Background: Measuring each protein's importance in signaling networks helps to identify the crucial proteins in a cellular process, find the fragile portion of the biology sy...
Wei Liu, Dong Li, Jiyang Zhang, Yunping Zhu, Fuchu...
BMCBI
2011
12 years 10 months ago
Assessing the functional coherence of modules found in multiple-evidence networks from Arabidopsis
Background: Combining multiple evidence-types from different information sources has the potential to reveal new relationships in biological systems. The integrated information ca...
Artem Lysenko, Michael Defoin-Platel, Keywan Hassa...