Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Background: The accomplishment of the various genome sequencing projects resulted in accumulation of massive amount of gene sequence information. This calls for a large-scale comp...
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
Background: Modern proteomes evolved by modification of pre-existing ones. It is extremely important to comparative biology that related proteins be identified as members of the s...
Adriano Barbosa-Silva, Venkata P. Satagopam, Reinh...