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TCBB
2011
12 years 11 months ago
A Partial Set Covering Model for Protein Mixture Identification Using Mass Spectrometry Data
—Protein identification is a key and essential step in mass spectrometry (MS) based proteome research. To date, there are many protein identification strategies that employ eithe...
Zengyou He, Can Yang, Weichuan Yu
BMCBI
2008
126views more  BMCBI 2008»
13 years 4 months ago
NITPICK: peak identification for mass spectrometry data
Background: The reliable extraction of features from mass spectra is a fundamental step in the automated analysis of proteomic mass spectrometry (MS) experiments. Results: This co...
Bernhard Y. Renard, Marc Kirchner, Hanno Steen, Ju...
BMCBI
2008
158views more  BMCBI 2008»
13 years 4 months ago
LC-MSsim - a simulation software for liquid chromatography mass spectrometry data
Background: Mass Spectrometry coupled to Liquid Chromatography (LC-MS) is commonly used to analyze the protein content of biological samples in large scale studies. The data resul...
Ole Schulz-Trieglaff, Nico Pfeifer, Clemens Gr&oum...
BMCBI
2010
152views more  BMCBI 2010»
13 years 4 months ago
A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry
Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
Chongle Pan, Byung-Hoon Park, William H. McDonald,...
BMCBI
2010
140views more  BMCBI 2010»
13 years 4 months ago
Quantification and deconvolution of asymmetric LC-MS peaks using the bi-Gaussian mixture model and statistical model selection
Background: Liquid chromatography-mass spectrometry (LC-MS) is one of the major techniques for the quantification of metabolites in complex biological samples. Peak modeling is on...
Tianwei Yu, Hesen Peng