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» A Randomized Numerical Aligner (rNA)
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LATA
2010
Springer
13 years 9 months ago
A Randomized Numerical Aligner (rNA)
With the advent of new sequencing technologies able to produce an enormous quantity of short genomic sequences, new tools able to search for them inside a references sequence genom...
Alberto Policriti, Alexandru I. Tomescu, Francesco...
BMCBI
2007
153views more  BMCBI 2007»
13 years 4 months ago
Lower bounds on multiple sequence alignment using exact 3-way alignment
Background: Multiple sequence alignment is fundamental. Exponential growth in computation time appears to be inevitable when an optimal alignment is required for many sequences. E...
Charles J. Colbourn, Sudhir Kumar
JCB
2007
107views more  JCB 2007»
13 years 4 months ago
Effects of Long-Range Correlations in DNA on Sequence Alignment Score Statistics
Long-range correlations in genomic base composition are a ubiquitous statistical feature among many eukaryotic genomes. In this article, these correlations are shown to substantia...
Philipp W. Messer, Ralf Bundschuh, Martin Vingron,...
ICASSP
2011
IEEE
12 years 8 months ago
EM-style optimization of hidden conditional random fields for grapheme-to-phoneme conversion
We have recently proposed an EM-style algorithm to optimize log-linear models with hidden variables. In this paper, we use this algorithm to optimize a hidden conditional random ï...
Georg Heigold, Stefan Hahn, Patrick Lehnen, Herman...
HPDC
2010
IEEE
13 years 5 months ago
MPIPairwiseStatSig: parallel pairwise statistical significance estimation of local sequence alignment
Sequence comparison is considered as a cornerstone application in bioinformatics, which forms the basis of many other applications. In particular, pairwise sequence alignment is a...
Ankit Agrawal, Sanchit Misra, Daniel Honbo, Alok N...