Surface-based techniques for protein comparison and classification typically require a compact surface representation, capable of effectively condensing its description. In this p...
Alessandra Lumini, Lorenzo Baldacci, Matteo Golfar...
Though most approaches to protein comparison are based on their structure, several studies produced evidence of a strict correlation between the surface characteristics of protein...
Lorenzo Baldacci, Matteo Golfarelli, Alessandra Lu...
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Background: Recent biological discoveries have shown that clustering large datasets is essential for better understanding biology in many areas. Spectral clustering in particular ...
Habil Zare, Parisa Shooshtari, Arvind Gupta, Ryan ...
Background: Recent approaches for predicting the three-dimensional (3D) structure of proteins such as de novo or fold recognition methods mostly rely on simplified energy potentia...