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BMCBI
2010
104views more  BMCBI 2010»
13 years 5 months ago
A novel scoring function for discriminating hyperthermophilic and mesophilic proteins with application to predicting relative th
Background: The ability to design thermostable proteins is theoretically important and practically useful. Robust and accurate algorithms, however, remain elusive. One critical pr...
Yunqi Li, C. Russell Middaugh, Jianwen Fang
MA
2010
Springer
172views Communications» more  MA 2010»
13 years 3 months ago
On Monte Carlo methods for Bayesian multivariate regression models with heavy-tailed errors
We consider Bayesian analysis of data from multivariate linear regression models whose errors have a distribution that is a scale mixture of normals. Such models are used to analy...
Vivekananda Roy, James P. Hobert
BMCBI
2010
182views more  BMCBI 2010»
13 years 5 months ago
L2-norm multiple kernel learning and its application to biomedical data fusion
Background: This paper introduces the notion of optimizing different norms in the dual problem of support vector machines with multiple kernels. The selection of norms yields diff...
Shi Yu, Tillmann Falck, Anneleen Daemen, Lé...