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BMCBI
2010
156views more  BMCBI 2010»
13 years 5 months ago
Protein complex prediction via verifying and reconstructing the topology of domain-domain interactions
Background: High-throughput methods for detecting protein-protein interactions enable us to obtain large interaction networks, and also allow us to computationally identify the as...
Yosuke Ozawa, Rintaro Saito, Shigeo Fujimori, Hisa...
BMCBI
2008
131views more  BMCBI 2008»
13 years 5 months ago
Modifying the DPClus algorithm for identifying protein complexes based on new topological structures
Background: Identification of protein complexes is crucial for understanding principles of cellular organization and functions. As the size of protein-protein interaction set incr...
Min Li, Jianer Chen, Jianxin Wang, Bin Hu, Gang Ch...
BMCBI
2008
170views more  BMCBI 2008»
13 years 5 months ago
Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data
Background: Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries o...
Tao Xu, LinFang Du, Yan Zhou
BMCBI
2007
227views more  BMCBI 2007»
13 years 5 months ago
Growing functional modules from a seed protein via integration of protein interaction and gene expression data
Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...
BMCBI
2008
120views more  BMCBI 2008»
13 years 5 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...