5 search results - page 1 / 1 » A classification model for distinguishing copy number varian... |
BMCBI
2010
13 years 4 months ago
2010
Background: Both somatic copy number alterations (CNAs) and germline copy number variants (CNVs) that are prevalent in healthy individuals can appear as recurrent changes in compa...
KES
2008
Springer
13 years 2 months ago
2008
Springer
Abstract. Motivation: Although studies have shown that genetic alterations are causally involved in numerous human diseases, still not much is known about the molecular mechanisms ...
BIOINFORMATICS
2010
13 years 4 months ago
2010
DNA copy number variants (CNV) are gains and losses of segments of chromosomes, and comprise an important class of genetic variation. Recently, various microarray hybridization ba...
BMCBI
2010
13 years 4 months ago
2010
Background: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleoti...
RECOMB
2003
Springer
14 years 4 months ago
2003
Springer
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...