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» A custom FPGA for the simulation of gene regulatory networks
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BMCBI
2007
116views more  BMCBI 2007»
13 years 5 months ago
Ranked Adjusted Rand: integrating distance and partition information in a measure of clustering agreement
Background: Biological information is commonly used to cluster or classify entities of interest such as genes, conditions, species or samples. However, different sources of data c...
Francisco R. Pinto, João A. Carriço,...
CEC
2010
IEEE
13 years 16 days ago
Parameter estimation with term-wise decomposition in biochemical network GMA models by hybrid regularized Least Squares-Particle
High-throughput analytical techniques such as nuclear magnetic resonance, protein kinase phosphorylation, and mass spectroscopic methods generate time dense profiles of metabolites...
Prospero C. Naval, Luis G. Sison, Eduardo R. Mendo...
BMCBI
2006
113views more  BMCBI 2006»
13 years 5 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
SIAMSC
2008
149views more  SIAMSC 2008»
13 years 5 months ago
Adaptive Discrete Galerkin Methods Applied to the Chemical Master Equation
In systems biology, the stochastic description of biochemical reaction kinetics is increasingly being employed to model gene regulatory networks and signalling pathways. Mathematic...
Peter Deuflhard, Wilhelm Huisinga, T. Jahnke, Mich...