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BMCBI
2010
115views more  BMCBI 2010»
13 years 4 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
BMCBI
2006
249views more  BMCBI 2006»
13 years 4 months ago
Gene functional similarity search tool (GFSST)
Background: With the completion of the genome sequences of human, mouse, and other species and the advent of high throughput functional genomic research technologies such as biomi...
Peisen Zhang, Jinghui Zhang, Huitao Sheng, James J...
BMCBI
2010
154views more  BMCBI 2010»
13 years 4 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
DIS
2007
Springer
13 years 11 months ago
Literature Based Discovery Support System and Its Application to Disease Gene Identification
We present an interactive discovery support system, which for a given starting concept of interest, discovers new, potentially meaningful relations with other concepts that have no...
Dimitar Hristovski, Borut Peterlin, Saso Dzeroski,...
BMCBI
2007
165views more  BMCBI 2007»
13 years 4 months ago
Ab initio identification of human microRNAs based on structure motifs
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
Markus Brameier, Carsten Wiuf