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BMCBI
2010
152views more  BMCBI 2010»
13 years 4 months ago
A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry
Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
Chongle Pan, Byung-Hoon Park, William H. McDonald,...
DAGM
2006
Springer
13 years 8 months ago
Probabilistic De Novo Peptide Sequencing with Doubly Charged Ions
Sequencing of peptides by tandem mass spectrometry has matured to the key technology for proteomics. Noise in the measurement process strongly favors statistical models like NovoHM...
Hansruedi Peter, Bernd Fischer, Joachim M. Buhmann
IMSCCS
2006
IEEE
13 years 10 months ago
Quality Assessment of Peptide Tandem Mass Spectra
Background: Tandem mass spectrometry has emerged as a cornerstone of high throughput proteomic studies owing in part to various high throughput search engines which are used to in...
Fang-Xiang Wu, Pierre Gagné, Arnaud Droit, ...
BMCBI
2010
117views more  BMCBI 2010»
13 years 4 months ago
Better score function for peptide identification with ETD MS/MS spectra
Background: Tandem mass spectrometry (MS/MS) has become the primary way for protein identification in proteomics. A good score function for measuring the match quality between a p...
Xiaowen Liu, Baozhen Shan, Lei Xin, Bin Ma
BMCBI
2006
124views more  BMCBI 2006»
13 years 4 months ago
HybGFS: a hybrid method for genome-fingerprint scanning
Background: Protein identification based on mass spectrometry (MS) has previously been performed using peptide mass fingerprinting (PMF) or tandem MS (MS/MS) database searching. H...
Kosaku Shinoda, Nozomu Yachie, Takeshi Masuda, Nao...