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» A joint model of regulatory and metabolic networks
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BMCBI
2007
215views more  BMCBI 2007»
13 years 5 months ago
Learning causal networks from systems biology time course data: an effective model selection procedure for the vector autoregres
Background: Causal networks based on the vector autoregressive (VAR) process are a promising statistical tool for modeling regulatory interactions in a cell. However, learning the...
Rainer Opgen-Rhein, Korbinian Strimmer
CEC
2010
IEEE
13 years 11 days ago
Parameter estimation with term-wise decomposition in biochemical network GMA models by hybrid regularized Least Squares-Particle
High-throughput analytical techniques such as nuclear magnetic resonance, protein kinase phosphorylation, and mass spectroscopic methods generate time dense profiles of metabolites...
Prospero C. Naval, Luis G. Sison, Eduardo R. Mendo...
APN
2006
Springer
13 years 7 months ago
From Petri Nets to Differential Equations - An Integrative Approach for Biochemical Network Analysis
Abstract. We report on the results of an investigation into the integration of Petri nets and ordinary differential equations (ODEs) for the modelling and analysis of biochemical n...
David Gilbert, Monika Heiner
ICTAI
2010
IEEE
13 years 3 months ago
The BioASP Library: ASP Solutions for Systems Biology
Abstract--Today's molecular biology is confronted with enormous amounts of data, generated by new high-throughput technologies, along with an increasing number of biological m...
Martin Gebser, Arne König, Torsten Schaub, Sv...
FM
2009
Springer
138views Formal Methods» more  FM 2009»
13 years 12 months ago
What Can Formal Methods Bring to Systems Biology?
This position paper argues that the operational modelling approaches from the formal methods community can be applied fruitfully within the systems biology domain. The results can ...
Nicola Bonzanni, K. Anton Feenstra, Wan Fokkink, E...